guarantees fertility by a large percentage
Doctors of impotence, infertility and IVF are betting on a new drug that will be presented in the coming days in the Saudi market, as it has been manufactured with genetic engineering and approved by the American Food and Drug Organization (FDA).
This drug, based on the estimates of infertility consultants, has achieved amazing results in the United States of America and Europe during the past two years, as the rate of pregnancy through it reached 45 percent, which is the highest rate that scientists have reached compared to similar drugs that did not exceed 20 percent.
Yesterday, Professor Samir Abbas, president of the Saudi Society for Fertility and Infertility, told Al-Sharq Al-Awsat: This drug, known as (Gonal F), is the latest findings of modern science in treating male and female infertility cases, and it is the hope for these patients during the third millennium.
The importance of this medicine - and the talk of Professor Samir Abbas - lies in the fact that the previous treatments are extracted from the urine of pregnant women or those who have reached menopause. Since this method is not guaranteed and has many drawbacks, the efforts of scientists in recent years have focused on producing a new type of drug using genetic engineering, and these efforts have culminated in the production of a drug that is manufactured with genetic engineering, where it is extracted from a type of bacteria.
The president of the Saudi Society for Fertility and Infertility confirms that this drug was used for the first time in the United States of America two years ago, as experiments have proven its success and effectiveness, and during the past year it has been dealt with through specialized centers in Saudi Arabia, and it has finally obtained the approval of officials in the Ministry of Health and was approved. For general circulation between doctors.
Professor Abbas pointed out that the results obtained in the specialized centers in the country are in line with the global ones, as they have proven successful in IVF with 30% and fertilization 80%. As for ovulation, the statistics indicate that the number of eggs produced by the ovaries after using This property has reached very high levels.
In this regard, a medical symposium will be held today in which a number of the best infertility doctors and treatment in the world will participate, and this event will be moderated by Professor Samir Abbas, President of the Saudi Society for Fertility and Infertility, Professor Hassan Saleh Jamal, President of the Saudi Society for Women and Childbirth, and Professor Abdulaziz Al-Mishary, Dean of the College Medicine at King Saud University in Riyadh, and a number of specialized Saudi doctors.
Talking about the new drug leads us to know what is meant by infertility, its causes in males and females, and modern methods of treatment, as it is defined as the absence of pregnancy after a full year of marital intercourse with the aim of conception, and the rate of this occurrence in the world ranges between 12 and 15 per cent of marriages, which is A problem that concerns the spouses together, not the woman alone.
Medical sources separate the causes of infertility into: 30% of them are for men, the same for other tubes and pelvic organs in women, 15% in women’s ovaries, 10% are unexplained infertility, and 5% are for unfamiliar reasons. The reasons for her low fertility, especially after she is over 35 years old.
Doctors now resort to diagnosing the foreseeable cases, and usually the beginning is by analyzing the semen and sperm counts for the man, and then examining the ovulation process and the fallopian tube in the woman. Male infertility Recent studies have revealed that the problem of male infertility is becoming more and more common in the world in general and in the Arab world in particular, and this is due to many reasons, especially: genetics, environment and weather conditions (increased temperature).
It is known that in normal cases the testicles produce about 60 to 80 million sperm per cubic centimeter, and reproduction does not occur if the sperm is less than 20 million. Despite this huge amount of production, only one sperm fertilizes the egg, as most of these animals cannot reach the egg to fertilize it in the fallopian tube inside the wife''s body for a relatively distance. The distance this sperm travels in relation to their size is equivalent to about a thousand kilometers relative to the size of a person, and if we know that the sperm travels this distance in only about twenty minutes, then we can estimate why most of them do not reach the intended target, which is the egg, just as it is not enough for the sperm to be Not only in huge numbers, but a large percentage of them must be healthy and able to move forward. One of the most common causes of male infertility is a lack of sperm count, poor movement or incomplete growth, and most of these reasons are available side by side, in addition to the lack of sperm, and these are prevalent in more than 20 percent of cases of male infertility, which is a result Testicular failure or obstruction of the vas deferens.
Therefore, doctors advise to refrain from smoking and alcoholic beverages, and not to expose the testicle to high temperatures, by taking a shower instead of a hot bath, and using loose underwear.
Female infertility causes female infertility several imbalances, the most important of which are: a defect in the ovaries, in the ducts, or in the uterus, and ovarian diseases are the most common, as they constitute 30 to 40 percent of cases of infertility in women, where the function of the ovaries is disturbed or ovulation is absent As a result of a defect in the secretion of the pituitary and ovarian hormones, which affect the growth and maturation of the egg and thus its release and release from the ovary to be snatched by the tube and complete its natural journey, or as a result of a congenital defect in the tissue formation of the ovaries or the occurrence of cysts around it.
The defect in the tubes, or what we call the fallopian tubes or the tubules, is also considered one of the main causes of female infertility, and with the same rate of ovarian diseases, where the tubes are considered to have a carrier function for the ovum first, where the tube grabs the egg from the ovary and is easy to slide inside, to meet the sperm and the fertilization is done, and then proceeding. The fertilized egg on its way to the uterus, and the defect is in the presence of a congenital malformation represented in the absence of the tube, for example, or the presence of a previous pelvic infection that led to a complete or partial blockage in the tube, in one or two ends, inside or outside the tube, to impede the normal functioning of the egg and then its arrival at the time Fitting to the womb for nesting, development and growth.
Cervical diseases represent 5 percent of these cases, where the cervix is the first barrier that the sperm must pass or penetrate to reach the uterus, and any change in the nature of these cervical secretions or cervical mucus may impede the entry of the sperm or prevent it or even kill it, This is due to the presence of previous infections or surgeries on the cervix, the influence of hormonal disorders, or even birth defects, which are few and rare.
Among the general causes are the presence of fibroids, polyps or adhesions as a result of infections, previous surgical interventions, or congenital anomalies, and all these factors impede the implantation of the fertilized egg in the endometrium and thus in the uterus to grow and enlarge.
There are immune reasons that contribute to preventing pregnancy, as there are immune bodies against sperm self in a man or in his blood or in a woman also in the blood or in the cervical mucus, which kills the sperm.
Finally, there are unexplained reasons, and it is that the spouses are healthy through the clinical, laboratory and investigative examination, and yet pregnancy does not occur. Tests that must be performed The doctor must conduct a number of tests to find out the causes of infertility in a man or a woman and then treat it, and the beginning is usually by assessing the ovarian functions, directly through blood hormone testing, and indirectly by examining the results of the effect of the hormones involved in the reproductive organs, such as measuring body temperature And taking a sample from the endometrium and a cytological swab from the vagina, following up the size and growth of the egg in the ovaries with ultrasound, seeing where the egg comes out from the ovary after laparoscopy, endoscopy, and seeing the internal female genital organs.
After completing the evaluation of the ovarian functions, the evaluation of the tubules or tubes and the uterus is carried out in stages The first is to inject the uterus and tubes with a colored material from the inside under x-rays. Then the uterus and tubes are injected with colored material under endoscopy into the abdominal cavity. After that, a salpingoscopy works and finally a hysteroscopy, where the uterine cavity and tubes can be seen from the inside, the path of the tubes, their permeability, and the extent to which they are free from deformities, adhesions, obstruction, or the presence of other diseases.
Finally, the cervix is evaluated by examining the cervical and cervical mucus in the middle of the cycle, studying it under a microscope, and taking a sample of cervical mucus a few hours after intercourse to study the vitality and activity of sperm in cervical secretions under a microscope, and antibodies can also be examined in both male and female.
Treatment To find the appropriate treatment for infertility, the cause must first be known, and therefore the chances of treatment with ovulation stimulants to stimulate the ovarian function or pituitary hormones through injection, and these two methods together give successes estimated in the medical community in 85 to 90 percent of cases.
There is surgical intervention, to remove the pathological cause affecting the function of the affected organ, and we mean here microsurgery, for example, to block the tubes, and surgical treatment contributes to loosening the adhesions, whether in the abdomen, uterus, tubes, or around the ovaries or cysts.
Artificial insemination is the best solution in cases of unexplained infertility or cases of suspicion of the presence of immune bodies, followed by the IVF technique of various kinds.
For a man, if there is a slight weakness in the sperm, the patient is advised to take vitamin C, E and zinc, which may lead to an improvement in the condition, and in more complex cases, the doctor resort to assistive fertilization treatments and IVF in the womb with ovulation induction, but if sperms are absent, then resort to Delicate surgeries to extract sperm from the testicle, as this is done with 100 percent success in cases of obstruction, and 60 percent in cases of testicular failure.
