It is possible that the main title of the report Chronic Granulomatous Disease is not the name you expected. Please check the synonyms listing to find the nate name(s) and disorder subdivision(s) covered by this report.
Synonyms
CGD
chronic dysphagocytosis
chronic granulomatous disease
congenital dysphagocytosis
fatal granulomatous disease of childhood
granulomatosis, chronic, familial
granulomatosis, septic, progressive
impotent neutrophil syndrome
Disorder Subdivisions
None
General Discussion
Chronic granulomatous disease (CGD) is a rare inherited primary immune deficiency disorder that affects certain white blood corpuscles (neutrophils, monocytes, macrophages, eosinophils). The disorder is characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, and bones may occur along with swollen areas of inflamed tissues known as granulomas that can be widely distributed. Symptoms usually begin in infancy or childhood. Individuals with mild forms of the disorder may not develop symptoms until the teens or adulthood. Chronic granulomatous disease is a genetic disorder and is caused by inherited defects in an important enzyme in white blood cells that manufactures oxidants for microbial killing.
